| Title: |
Endoscopic imaging System |
| Category: |
Faculty |
| Intellectual Property: |
The intellectual property will be placed in the public domain |
| Year: |
2009 |
| Semester: |
Fall |
| Sponsor Name: |
Jennifer Barton |
| Sponsoring advisors: |
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| Sponsor URL: |
http://www.engr.arizona.edu/~BMEoptics/ |
| Sponsor Information: |
Jennifer Barton is head of the department of Biomedical Engineering and professor of Electrical and Computer Engineering, Optical Sciences, and Agricultural and Biosystems Engineering. She is also Assistant Director of the BIO5 Institute. Her lab is located in the Keating (BIO5) building, one block north of Speedway and two blocks east of the AME building. Her expertise areas are optical imaging technology development, and applications to early cancer detection. |
| ITAR Restriction: |
No |
| Scope of work: |
Students will design, specify components, assemble, and test a tri-modality endoscopic imaging system that is capable of obtaining simultaneous optical coherence tomography (OCT), laser induced fluorescence (LIF), and surface magnifying chromoendoscopy (SME) images. The endoscope itself already exists, as does the OCT subsystem. Students will be responsible for 1) designing the SME and LIF subsystems, 2) integrating these subsystems into an overall tri-modality system, and 3) testing/image processing. Each of these tasks is described in more detail below:
1) the SME subsystem will include a light source that must be efficiently coupled into a fiber bundle, and a CCD camera which must efficiently and with minimal distortions capture the image relayed from the tissue through another fiber bundle. The system must also be set up to to perform fluorescence imaging using a dichroic beam splitter. The LIF subsystem includes an illumination laser and a spectrometer to collect remitted fluorescence emission. The optical and mechanical design must be performed
for the two subsystems.
2) Integration will involve physically locating the subsystems on the optical table in an efficient manner, and modifying existing system software (C++) to add LIF and SME capability in synchrony with OCT imaging and motion control of the endoscope.
3) The SME images obtained will be overlapping snapshots obtained while the endoscope is moving. Image stitching must be performed to obtain a continuous surface image. The endoscopic system is designed to image small tubular structures such as the distal colon of the mouse. Students will test optical and image processing performance with tissue "phantoms" (surrogate non-biological test subjects). Student may participate in in vivo testing if they desire and if they obtain training certificates.
More information is in the attached proposal. Students will perform specific aim 1, "system design" and "image processing" tasks. |
| Project summary: |
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| Disciplines: |
Agricultural and Biosystems Engineering (1)
Electrical Engineering (2)
Optical Sciences and Engineering (2) |
| Skills: |
optical system design
electronic device (CCD and motion) integration
image processing (image stitching)
C++ programming |
| Additional resources: |
Fully equipped biomedical optics lab, with optical table, optics, opto-mechanics, Zemax optical design software, personal computers with some image processing software. |
| Key Contact Name: |
Jennifer Barton |
| Key Contact Email: |
barton@u.arizona.edu |
| Key Contact Phone: |
621-4116 |
| Project URL: |
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| Mentor Name: |
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| Mentor Email: |
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| Mentor Phone: |
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